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Midazolam Nasal Spray and Depression

Result of checking the interaction of drug Midazolam Nasal Spray and disease Depression for safety when used together.

Check result:

Midazolam Nasal Spray <> Depression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Benzodiazepines depress the central nervous system and may cause or exacerbate mental depression and cause suicidal behavior and ideation. Episodes of mania and hypomania have also been reported in depressed patients treated with some of these agents. Therapy with benzodiazepines should be administered cautiously in patients with a history of depression or other psychiatric disorders. Patients should be monitored for any changes in mood or behavior. It may be prudent to refrain from dispensing large quantities of medication to these patients.

References:

"Product Information. Klonopin (clonazepam)." Roche Laboratories, Nutley, NJ.
"Product Information. Restoril (temazepam)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
"Product Information. Librium (chlordiazepoxide)." Roche Laboratories, Nutley, NJ.
"Product Information. Tranxene (clorazepate)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Ativan (lorazepam)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Dalmane (flurazepam)." Roche Laboratories, Nutley, NJ.
"Product Information. Serax (oxazepam)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. ProSom (estazolam)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Valium (diazepam)." Roche Laboratories, Nutley, NJ.
"Product Information. Xanax (alprazolam)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Halcion (triazolam)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Doral (quazepam)." Wallace Laboratories, Cranbury, NJ.