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Miconazole oral buccal and Liver disease

Result of checking the interaction of drug Miconazole oral buccal and disease Liver disease for safety when used together.

Check result:
Miconazole oral buccal <> Liver disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of miconazole in patients with liver disease has not been adequately studied, although it is known that miconazole is primarily metabolized by the liver. Therapy with miconazole should be administered cautiously in patients with liver disease, and the dosing adjusted or discontinued according to clinical response.

References:
  • "Product Information. Monistat (miconazole)." Ortho Pharmaceutical Corporation, Raritan, NJ.
  • Daneshmend TK, Warnock DW "Clinical pharmacokinetics of systemic antifungal drugs." Clin Pharmacokinet 8 (1983): 17-42
  • Lewi PJ, Boelaert J, Daneels R, et al "Pharmacokinetic profile of intravenous miconazole in man." Eur J Clin Pharmacol 10 (1976): 49-54
Miconazole oral buccal

Generic Name: miconazole

Brand Name: Oravig, Monistat IV, Oravig

Synonyms: Miconazole oral (buccal), Miconazole (Oral)

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