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Metronidazole topical and Blood dyscrasias

Result of checking the interaction of drug Metronidazole topical and disease Blood dyscrasias for safety when used together.

Check result:

Metronidazole topical <> Blood dyscrasias

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Metronidazole may be systemically absorbed when applied to the skin or mucosal membranes. The use of metronidazole has rarely been associated with hematologic adverse effects such as mild, transient leukopenia, thrombocytopenia, and bone marrow aplasia. The manufacturers recommend that therapy with metronidazole be administered cautiously in patients with evidence of or a history of blood dyscrasias.

References:

Smith JA "Neutropenia associated with metronidazole therapy." Can Med Assoc J 123 (1980): 202
"Product Information. Metrogel (metronidazole)." Galderma Laboratories Inc, Fort Worth, TX.
White CM, Price JJ, Hunt KM "Bone marrow aplasia associated with metronidazole." Br Med J 280 (1980): 647

Metronidazole topical

Generic Name: metronidazole topical

Brand Name: MetroCream, MetroGel, MetroGel Pump, MetroLotion, Noritate, Rosadan, MetroGel-Vaginal, Nuvessa, Vandazole

Synonyms: MetroNIDAZOLE (Topical)

What is Metronidazole topical?