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Metronidazole Oral, Intravenous and Dialysis
Result of checking the interaction of drug Metronidazole Oral, Intravenous and disease Dialysis for safety when used together.
Check result:
Metronidazole Oral, Intravenous <> Dialysis
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Metronidazole and its metabolites are moderately removed by hemodialysis. Doses should either be scheduled for administration after dialysis or supplemental doses be given after dialysis.
References:
- Kreeft JH, Ogilvie RI, Dufresne LR "Metronidazole kinetics in dialysis patients." Surgery 93 (1983): 149-53
- "Product Information. Flagyl (metronidazole)." Searle, Skokie, IL.
- Roux AF, Moirot E, Delhotal B, et al "Metronidazole kinetics in patients with acute renal failure on dialysis: a cumulative study." Clin Pharmacol Ther 36 (1984): 363-8
- Somogyi A, Kong C, Sabto J, Gurr FW, Spicer WJ, McLean AJ "Disposition and removal of metronidazole in patients undergoing haemodialysis." Eur J Clin Pharmacol 25 (1983): 683-7
- Lau AH, Chang CW, Sabatini S "Hemodialysis clearance of metronidazole and its metabolites." Antimicrob Agents Chemother 29 (1986): 235-8
Metronidazole Oral, Intravenous
Generic Name: metronidazole
Brand Name: Flagyl, MetroGel, FIRST Metronidazole, Flagyl 375
Synonyms: Metronidazole, MetroNIDAZOLE (Systemic)
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