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Metronidazole Oral, Intravenous and Blood dyscrasias

Result of checking the interaction of drug Metronidazole Oral, Intravenous and disease Blood dyscrasias for safety when used together.

Check result:

Metronidazole Oral, Intravenous <> Blood dyscrasias

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of nitroimidazoles (e.g., metronidazole, tinidazole) has rarely been associated with hematologic adverse effects such as mild, transient leukopenia, thrombocytopenia, and bone marrow aplasia. The manufacturers recommend that therapy with nitroimidazoles be administered cautiously in patients with evidence of or a history of blood dyscrasias, and that total and differential leukocyte counts be performed before and after treatment with these drugs, particularly in patients receiving repeated courses of therapy.

References:

White CM, Price JJ, Hunt KM "Bone marrow aplasia associated with metronidazole." Br Med J 280 (1980): 647
"Product Information. Tindamax (tinidazole)." Presutti Laboratories Inc, Arlington Heights, IL.
"Product Information. Flagyl (metronidazole)." Searle, Skokie, IL.
Smith JA "Neutropenia associated with metronidazole therapy." Can Med Assoc J 123 (1980): 202

Metronidazole Oral, Intravenous

Generic Name: metronidazole

Brand Name: Flagyl, MetroGel, FIRST Metronidazole, Flagyl 375

Synonyms: Metronidazole, MetroNIDAZOLE (Systemic)

What is Metronidazole Oral, Intravenous?