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Metoprolol and hydrochlorothiazide and Asthma/COPD

Result of checking the interaction of drug Metoprolol and hydrochlorothiazide and disease Asthma/COPD for safety when used together.

Check result:
Metoprolol and hydrochlorothiazide <> Asthma/COPD
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with bronchospastic disease, should, in general, not receive beta blockers, including cardioselective beta-blockers. Because of the relative beta-1 selectivity, cardioselective beta-blockers may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. Because beta-1 selectivity is not absolute, the lowest possible dose of these agents should be used. Consider administering in smaller doses to avoid the higher plasma levels associated with the longer dosing intervals. If dosage must be increased, dividing the dose should be considered to achieve lower peak blood levels. It is recommended to have bronchodilators, including beta-2 agonists, readily available or administered concomitantly if necessary.

Metoprolol and hydrochlorothiazide

Generic Name: hydrochlorothiazide / metoprolol

Brand Name: Dutoprol, Lopressor HCT

Synonyms: Hydrochlorothiazide and metoprolol, Metoprolol and Hydrochlorothiazide

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