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Methyldopa and Hydrochlorothiazide and Peripheral edema

Result of checking the interaction of drug Methyldopa and Hydrochlorothiazide and disease Peripheral edema for safety when used together.

Check result:
Methyldopa and Hydrochlorothiazide <> Peripheral edema
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Methyldopa may cause edema or weight gain associated with sodium retention. Therapy with methyldopa should be administered cautiously in patients adversely affected by sodium and water retention.

References:
  • Varkel Y, Braester A, Nusem D, Shkolnik T "Methyldopa-induced syndrome of inappropriate antidiuretic hormone-secretion and bone marrow granulomatosis." Drug Intell Clin Pharm 22 (1988): 700-1
  • "Product Information. Aldomet (methyldopa)." Merck & Co, Inc, West Point, PA.
Methyldopa and Hydrochlorothiazide

Generic Name: hydrochlorothiazide / methyldopa

Brand Name: Aldoril 15, Aldoril 25, Aldoril D30, Aldoril D50

Synonyms: Hydrochlorothiazide and methyldopa

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