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Methergine (Methylergonovine Injection) and Hypertension

Result of checking the interaction of drug Methergine (Methylergonovine Injection) and disease Hypertension for safety when used together.

Check result:

Methergine (Methylergonovine Injection) <> Hypertension

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of the amine ergot alkaloids, ergonovine and methylergonovine, is considered by some clinicians to be contraindicated in patients with hypertension. These agents can cause hypertension, particularly when administered IV undiluted or at an excessive rate or when used in conjunction with regional anesthesia or vasoconstrictors. Headaches, seizures, cerebrovascular accidents and death have been associated with the hypertensive episodes. Patients with chronic hypertension or preeclampsia may be at increased risk for these complications. Of the two agents, methylergonovine has less tendency to cause hypertension, although preferably neither agent should be administered to at- risk patients.

References:

"Product Information. Ergotrate Maleate (ergonovine)." Bedford, Bedford, OH.
American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):

Methergine (Methylergonovine Injection)

Generic Name: methylergonovine

Brand Name: Methergine

Synonyms: Methergine (oral and injection), Methergine

What is Methergine (Methylergonovine Injection)?