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Mercaptopurine and Renal dysfunction

Result of checking the interaction of drug Mercaptopurine and disease Renal dysfunction for safety when used together.

Check result:
Mercaptopurine <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Mercaptopurine is excreted in the urine as unchanged drug and metabolites. Renal elimination may be reduced in patients with impaired renal function. Therapy with mercaptopurine should be initiated at a reduced dosage in patients with compromised renal function. Clinical monitoring of renal function is recommended.

References:
  • "Product Information. Purinethol (mercaptopurine)." Glaxo Wellcome, Research Triangle Pk, NC.
Mercaptopurine

Generic Name: mercaptopurine

Brand Name: Purixan, Purinethol

Synonyms: n.a.

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