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Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Suspension and Anticholinergic effects

Result of checking the interaction of drug Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Suspension and disease Anticholinergic effects for safety when used together.

Check result:
Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Suspension <> Anticholinergic effects
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Antihistamines often have anticholinergic activity, to which elderly patients are particularly sensitive. Therapy with antihistamines should be administered cautiously, if at all, in patients with preexisting conditions that are likely to be exacerbated by anticholinergic activity, such as urinary retention or obstruction; angle-closure glaucoma, untreated intraocular hypertension, or uncontrolled primary open-angle glaucoma; and gastrointestinal obstructive disorders. Conventional, first-generation antihistamines such as the ethanolamines (bromodiphenhydramine, carbinoxamine, clemastine, dimenhydrinate, diphenhydramine, doxylamine, phenyltoloxamine) tend to exhibit substantial anticholinergic effects. In contrast, the newer, relatively nonsedating antihistamines (e.g., cetirizine, fexofenadine, loratadine) reportedly have low to minimal anticholinergic activity at normally recommended dosages and may be appropriate alternatives.

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Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Suspension

Generic Name: acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine

Brand Name: Dimetapp Multi-Symptom Cold and Flu, GNP Tussin Night Time, Cold Head Congestion Nighttime, Cold Multi-Symptom Nighttime, Comtrex Cold & Cough Nighttime, Theraflu Severe Cold Nighttime, Tylenol Cold Head Congestion, Tylenol Children’s Plus Flu, Tylenol Children’s Plus Multi-Symptom Cold

Synonyms: Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Liquid

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