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Megestrol Acetate and Hyperadrenocorticalism

Result of checking the interaction of drug Megestrol Acetate and disease Hyperadrenocorticalism for safety when used together.

Check result:

Megestrol Acetate <> Hyperadrenocorticalism

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Megestrol appears to have glucocorticoid activity and may aggravate conditions of hyperadrenocorticalism. Clinical cases of overt Cushing's syndrome and adrenal insufficiency have been reported in association with the chronic use of megestrol.

References:

Leinung MC, Liporace R, Miller CH "Induction of adrenal suppression by megestrol acetate in patients with AIDS." Ann Intern Med 122 (1995): 843-5
Caparros GC, Zambrana JL, Delgado-Fernandez M, Diez F "Megestrol-induced Cushing syndrome." Ann Pharmacother 35 (2001): 1208-10
"Product Information. Megace (megestrol)." Bristol-Myers Squibb, Princeton, NJ.
Koch CA, Pacak K "Abnormal ACTH-stimulation test in a patient with AIDS: adrenal insufficiency or toxoplasmosis?" Endocr Regul 35 (2001): 91-3

Megestrol Acetate

Generic Name: megestrol

Brand Name: Megace ES, Megace

Synonyms: Megestrol

What is Megestrol Acetate?