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Maxalt-MLT and Liver disease

Generic Name: rizatriptan
Dosage Forms: tablet, orally disintegrating
Other Brand Names: Maxalt , Maxalt-MLT

Result of checking the interaction of drug Maxalt-MLT and disease Liver disease for safety when used together.

Check result:

Maxalt-MLT <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Rizatriptan is primarily metabolized by the liver. Following oral administration in patients with alcoholic cirrhosis of the liver, the plasma concentrations of rizatriptan were not significantly altered in patients with mild hepatic impairment but were approximately 30% higher in patients with moderate hepatic impairment compared to healthy controls. Therapy with rizatriptan should be administered cautiously in patients with significantly impaired hepatic function. A lower initial dosage may be appropriate.

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