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Maraviroc and Renal impairment

Result of checking the interaction of drug Maraviroc and disease Renal impairment for safety when used together.

Check result:

Maraviroc <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

An increased risk of postural hypotension may occur in patients with severe renal impairment or those with end-stage renal disease, due to increased exposure to maraviroc. This drug should be used with caution in these patients only if they are not receiving a concomitant potent CYP3A inhibitor or inducer, and therapy should be considered only when there is no other treatment option. A dose reduction might be necessary if any symptoms of postural hypotension are experienced. No studies have been performed in patients with severe renal impairment (CrCl < 30 mL/min) or ESRD who are taking concomitant CYP3A inhibitors or inducers, and maraviroc is contraindicated on these patients.

Maraviroc

Generic Name: maraviroc

Brand Name: Selzentry

Synonyms: n.a.

What is Maraviroc?