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Maprotiline Hydrochloride and Neutropenia

Result of checking the interaction of drug Maprotiline Hydrochloride and disease Neutropenia for safety when used together.

Check result:

Maprotiline Hydrochloride <> Neutropenia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of tetracyclic antidepressants has been associated with neutropenia (ANC < 500/mm3) and agranulocytosis (ANC < 500/mm3) with associated signs and symptoms,( e.g., fever, infection, etc.). Patients with preexisting neutropenia or agranulocytosis should be monitored closely during therapy for further decreases in white blood cell (WBC) counts. Treatment should be discontinued in any patient who develops a sore throat, fever, stomatitis, or other signs of infection along with a low WBC count.

References:

Montgomery SA "Safety of mirtazapine: a review." Int Clin Psychopharmacol 10(suppl 4 (1995): 37-45
Settle EC "Antidepressant drugs: disturbing and potentially dangerous adverse effects." J Clin Psychiatry 59 Suppl 16 (1998): 25-30
"Product Information. Remeron (mirtazapine)." Organon, West Orange, NJ.

Maprotiline Hydrochloride

Generic Name: maprotiline

Brand Name: Ludiomil

Synonyms: Maprotiline

What is Maprotiline Hydrochloride?