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Lorlatinib and Severe renal impairment

Result of checking the interaction of drug Lorlatinib and disease Severe renal impairment for safety when used together.

Check result:
Lorlatinib <> Severe renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The recommended dose of lorlatinib has not been established for patients with severe renal impairment. No dose adjustment is recommended for patients with mild or moderate renal impairment (creatinine clearance [CrCl] 30 to 89 mL/min estimated by Cockcroft-Gault).

Lorlatinib

Generic Name: lorlatinib

Brand Name: Lorbrena

Synonyms: n.a.

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