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Lorazepam Oral Concentrate and Closed-angle glaucoma

Result of checking the interaction of drug Lorazepam Oral Concentrate and disease Closed-angle glaucoma for safety when used together.

Check result:

Lorazepam Oral Concentrate <> Closed-angle glaucoma

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The manufacturers consider the use of benzodiazepines to be contraindicated in patients with acute angle-closure glaucoma or untreated open-angle glaucoma. These agents do not possess anticholinergic activity but have very rarely been associated with increased intraocular pressure.

References:

"Product Information. Restoril (temazepam)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
"Product Information. Xanax (alprazolam)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Doral (quazepam)." Wallace Laboratories, Cranbury, NJ.
"Product Information. Dalmane (flurazepam)." Roche Laboratories, Nutley, NJ.
"Product Information. ProSom (estazolam)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Versed (midazolam)." Roche Laboratories, Nutley, NJ.
"Product Information. Valium (diazepam)." Roche Laboratories, Nutley, NJ.
"Product Information. Tranxene (clorazepate)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Librium (chlordiazepoxide)." Roche Laboratories, Nutley, NJ.
"Product Information. Ativan (lorazepam)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Fraunfelder FT, Fraunfelder FW; Randall JA "Drug-Induced Ocular Side Effects 5th" Boston, MA: Butterworth-Heinemann (2001):
"Product Information. Serax (oxazepam)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Klonopin (clonazepam)." Roche Laboratories, Nutley, NJ.
"Product Information. Halcion (triazolam)." Pharmacia and Upjohn, Kalamazoo, MI.