Lomotil (Diphenoxylate and Atropine Solution) and Hepatic/renal dysfunction
Result of checking the interaction of drug Lomotil (Diphenoxylate and Atropine Solution) and disease Hepatic/renal dysfunction for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Therapy with antiperistaltic agents should be administered with extreme caution in patients with hepatorenal disease or abnormal liver enzymes. Antiperistaltic agents are metabolized by the liver (diphenoxylate to an active form) and primarily excreted in the feces. Hepatic coma can be precipitated.
- "Product Information. Imodium (loperamide)." Janssen Pharmaceutica, Titusville, NJ.
- "Product Information. Kaopectate (attapulgite)." Pharmacia and Upjohn, Kalamazoo, MI.
- "Product Information. Pepto-Bismol (bismuth subsalicylate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH.
Generic Name: atropine / diphenoxylate
Brand Name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Lomotil