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Lithium Carbonate ER Tablets and Sodium depletion

Result of checking the interaction of drug Lithium Carbonate ER Tablets and disease Sodium depletion for safety when used together.

Check result:

Lithium Carbonate ER Tablets <> Sodium depletion

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Lithium decreases sodium reabsorption by the renal tubules which could lead to sodium depletion. Therapy with lithium should be administered cautiously in patients with preexisting sodium depletion as the risk of lithium toxicity is increased. Lower dosages may be required. Patients should maintain a normal diet, including salt, and an adequate fluid intake. Monitoring lithium serum concentrations is recommended.

References:

"Product Information. Lithobid (lithium)." Ciba Pharmaceuticals, Summit, NJ.
Depner TA "Nephrotic syndrome secondary to lithium therapy." Nephron 30 (1982): 286-9
Reisberg B, Gershon S "Side effects associated with lithium therapy." Arch Gen Psychiatry 36 (1979): 879-87
"Product Information. Eskalith (lithium)." SmithKline Beecham, Philadelphia, PA.
Wood IK, Parmalee DX, Foreman JW "Lithium-induced nephrotic syndrome." Am J Psychiatry 146 (1989): 84-7
Hansen HE, Hestbech J, Olsen S, Amdisen A "Renal function and renal pathology in patients with lithium-induced impairment of renal concentrating ability." Dial Transplant Nephrol 14 (1977): 518-27
Hurtig DL, Dyson WL "Lithium toxicity enhanced by diuresis." N Engl J Med 290 (1974): 748-9

Lithium Carbonate ER Tablets

Generic Name: lithium

Brand Name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR

Synonyms: Lithium

What is Lithium Carbonate ER Tablets?