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Lithium Carbonate ER Tablets and Hypothyroidism

Result of checking the interaction of drug Lithium Carbonate ER Tablets and disease Hypothyroidism for safety when used together.

Check result:

Lithium Carbonate ER Tablets <> Hypothyroidism

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of lithium has been associated with hypothyroidism in 5% to 15% of patient as it blocks the release of thyroxine (T4) and triiodothyronine (T3) mediated by thyrotropin. Therapy with lithium should be administered cautiously in patients with preexisting hypothyroidism. Careful monitoring of the thyroid function is recommended and supplemental thyroid treatment may be required.

References:

Waldman SA, Park D "Myxedema coma associated with lithium therapy." Am J Med 87 (1989): 355-7
"Product Information. Eskalith (lithium)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Lithobid (lithium)." Ciba Pharmaceuticals, Summit, NJ.
Terao T "Subclinical hypothyroidism in recurrent mania." Biol Psychiatry 33 (1993): 853-4
Shopsin B, Shenkman L, Blum M, Hollander CS "Iodine and lithium-induced hypothyroidism." Am J Med 55 (1973): 695-8
Schou M, Baastrup PC, Grof P, Weis P, Angst J "Pharmacological and clinical problems of lithium prophylaxis." Br J Psychiatry 116 (1970): 615-9

Lithium Carbonate ER Tablets

Generic Name: lithium

Brand Name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR

Synonyms: Lithium

What is Lithium Carbonate ER Tablets?