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Lithium Carbonate ER Tablets and Dehydration

Result of checking the interaction of drug Lithium Carbonate ER Tablets and disease Dehydration for safety when used together.

Check result:

Lithium Carbonate ER Tablets <> Dehydration

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Lithium reduces the ability of the kidney to concentrate urine and produces a mild diabetes insipidus and polyuria. Therefore, patients with preexisting dehydration are more prone to lithium retention and toxicity. Therapy with lithium should be administered cautiously in dehydrated patients and may need to be discontinued until improvement in hydration status. Careful monitoring of lithium levels are recommended. Patients with sweating, diarrhea or concomitant infection with fever may need a temporary reduction or cessation of medication.

References:

Vestergaard P, Amdisen A, Schou M "Clinically significant side effects of lithium treatment." Acta Psychiatr Scand 62 (1980): 193-200
Martinez EJ, Sinnott JT, 4th Rodriguez-Paz G, Oehler RL "Lithium-induced nephrogenic diabetes insipidus treated with indomethacin." South Med J 86 (1993): 971-3
Walker RG "Lithium nephrotoxicity." Kidney Int Suppl 42 (1993): s93-8
Martin A "Clinical management of lithium-induced polyuria." Hosp Community Psychiatry 44 (1993): 427-8
Ramsey TA, Mendels J, Stokes JW, Fitzgerald RG "Lithium carbonate and kidney function." JAMA 219 (1972): 1446-9
"Product Information. Lithobid (lithium)." Ciba Pharmaceuticals, Summit, NJ.
"Product Information. Eskalith (lithium)." SmithKline Beecham, Philadelphia, PA.
Hansen HE, Hestbech J, Olsen S, Amdisen A "Renal function and renal pathology in patients with lithium-induced impairment of renal concentrating ability." Dial Transplant Nephrol 14 (1977): 518-27

Lithium Carbonate ER Tablets

Generic Name: lithium

Brand Name: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR

Synonyms: Lithium

What is Lithium Carbonate ER Tablets?