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Amiodarone Intravenous, Oral and Neurologic dysfunction

Result of checking the interaction of drug Amiodarone Intravenous, Oral and disease Neurologic dysfunction for safety when used together.

Check result:

Amiodarone Intravenous, Oral <> Neurologic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Reversible and dose-related nervous system toxicity such as dizziness, paresthesia, tremor and involuntary movements, lack of coordination, abnormal gait and ataxia is commonly noted in patients receiving amiodarone. Therapy with amiodarone should be administered cautiously and dosage modifications considered in patients with or predisposed to neurologic dysfunction.

References:

"Product Information. Cordarone Intravenous (amiodarone)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Trohman RG, Castellanos D, Castellanos A, Kessler KM "Amiodarone-induced delirium." Ann Intern Med 108 (1988): 68-9
Manolis AS, Tordjman T, Mack KD, Estes NA III "Atypical pulmonary and neurologic complications of amiodarone in the same patient." Arch Intern Med 147 (1987): 1805-9
Pellissier JF, Pouget J, Cros D, De Victor B, Serratrice G, Toga M "Peripheral neuropathy induced by amiodarone chlorhydrate: a clinicopathological study." J Neurol Sci 63 (1984): 251-66
Roth RF, Itabashi H, Louie J, Anderson T, Narahara KA "Amiodarone toxicity: myopathy and neuropathy." Am Heart J 119 (1990): 1223-4
"Product Information. Cordarone (amiodarone)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Werner EG, Olanow CW "Parkinsonism and amiodarone therapy." Ann Neurol 25 (1989): 630-2
Lim PK, Trewby PN, Storey GC, Holt DW "Neuropathy and fatal hepatitis in a patient receiving amiodarone." Br Med J 288 (1984): 1638-9
Palakurthy PR, Iyer V, Meckler RJ "Unusual neurotoxicity associated with amiodarone therapy." Arch Intern Med 147 (1987): 881-4

Amiodarone Intravenous, Oral

Generic Name: amiodarone

Brand Name: Pacerone, Cordarone, Nexterone

Synonyms: Amiodarone

What is Amiodarone Intravenous, Oral?