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Lidocaine and Prilocaine and Renal/hepatic dysfunction

Result of checking the interaction of drug Lidocaine and Prilocaine and disease Renal/hepatic dysfunction for safety when used together.

Check result:

Lidocaine and Prilocaine <> Renal/hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Prilocaine topical is absorbed through intact skin and mucosal membranes. Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of prilocaine. Prilocaine is metabolized by the liver and to some extent by the kidney. The pharmacokinetic disposition of prilocaine is altered by changes in hepatic and renal function. Therapy with prilocaine topical should be administered cautiously and dosing modified for patients with compromised hepatic and renal function.

Lidocaine and Prilocaine

Generic Name: lidocaine / prilocaine topical

Brand Name: Emla, Emla Anesthetic Disc, Livixil Pak, AgonEaze, Prizopak, LiproZonePak, Medolor Pak, Anodyne LPT

Synonyms: Lidocaine and prilocaine topical

What is Lidocaine and Prilocaine?