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Levodopa, Carbidopa, and Entacapone and GI bleeding

Result of checking the interaction of drug Levodopa, Carbidopa, and Entacapone and disease GI bleeding for safety when used together.

Check result:
Levodopa, Carbidopa, and Entacapone <> GI bleeding
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of levodopa, especially in combinations with carbidopa, has been associated with an increase in the frequency of gastrointestinal hemorrhage. Therapy with levodopa should be administered cautiously in patients with a history of peptic ulcer disease or gastrointestinal hemorrhage.

References:
  • "Product Information. Sinemet CR (carbidopa-levodopa)." Dupont Pharmaceuticals, Wilmington, DE.
  • "Product Information. Sinemet (carbidopa-levodopa)." DuPont Pharmaceuticals, Wilmington, DE.
Levodopa, Carbidopa, and Entacapone

Generic Name: carbidopa / entacapone / levodopa

Brand Name: Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75, Stalevo

Synonyms: Carbidopa, entacapone, and levodopa

Interaction with food and lifestyle