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Acetaminophen, caffeine, and magnesium salicylate and G-6-PD deficiency

Result of checking the interaction of drug Acetaminophen, caffeine, and magnesium salicylate and disease G-6-PD deficiency for safety when used together.

Check result:
Acetaminophen, caffeine, and magnesium salicylate <> G-6-PD deficiency
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Salicylates, particularly aspirin, may cause or aggravate hemolysis in patients with pyruvate kinase or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency. However, this effect has not been clearly established. Until more data are available, therapy with salicylates should be administered cautiously in patients with G-6-PD deficiency. The same precaution should also be observed with the use of related agents such as salicylamide because of their structural and pharmacological similarities to salicylate.

References:
  • "Product Information. Salflex (salsalate)." Carnrick Laboratories Inc, Cedar Knolls, NJ.
  • "Product Information. Rexolate (sodium thiosalicylate)" Hyrex Pharmaceuticals, Memphis, TN.
  • "Product Information. Ecotrin (aspirin)." SmithKline Beecham, Philadelphia, PA.
Acetaminophen, caffeine, and magnesium salicylate

Generic Name: acetaminophen / caffeine / magnesium salicylate

Brand Name: KneeRelief

Synonyms: n.a.

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