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Ledipasvir and sofosbuvir and Renal impairment

Result of checking the interaction of drug Ledipasvir and sofosbuvir and disease Renal impairment for safety when used together.

Check result:
Ledipasvir and sofosbuvir <> Renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of products containing ledipasvir and sofosbuvir in patients with mild or moderate renal impairment does not require dosage adjustment. Exercise care when using in patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2) or ESRD requiring hemodialysis as the safety and efficacy has not been established, and no dosage recommendation can be given for these patients.

Ledipasvir and sofosbuvir

Generic Name: ledipasvir / sofosbuvir

Brand Name: Harvoni

Synonyms: Ledipasvir and Sofosbuvir

Ledipasvir and sofosbuvir <> Renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The safety and efficacy of sofosbuvir as a single agent have not been established in patients with severe renal impairment (eGFR less than 30 mL/min/1.73m2) or ESRD requiring hemodialysis. No dosage recommendation can be given for patients with severe renal impairment or ESRD. No dosage adjustment is necessary for patients with mild or moderate renal impairment.

Ledipasvir and sofosbuvir

Generic Name: ledipasvir / sofosbuvir

Brand Name: Harvoni

Synonyms: Ledipasvir and Sofosbuvir

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