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Lapatinib Ditosylate and QT prolongation

Result of checking the interaction of drug Lapatinib Ditosylate and disease QT prolongation for safety when used together.

Check result:

Lapatinib Ditosylate <> QT prolongation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

QT prolongation was observed in patients treated with certain EGFR inhibitors. These agents should be administered with caution in patients with congenital long QTc syndrome, congestive heart failure, electrolyte abnormalities, or those who are taking medications known to prolong the QTc interval. Serum electrolytes should be corrected prior to initiating therapy with these agents. Periodic monitoring of ECGs and electrolytes is recommended in these patients. Permanently discontinue the use of these agents in patients who develop QTc interval prolongation with signs/symptoms of life-threatening arrhythmia.

Lapatinib Ditosylate

Generic Name: lapatinib

Brand Name: Tykerb

Synonyms: Lapatinib

What is Lapatinib Ditosylate?