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Acetaminophen, butalbital, caffeine, and codeine and PKU

Result of checking the interaction of drug Acetaminophen, butalbital, caffeine, and codeine and disease PKU for safety when used together.

Check result:
Acetaminophen, butalbital, caffeine, and codeine <> PKU
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Several oral acetaminophen and acetaminophen-combination products, particularly flavored chewable tablets, contain the artificial sweetener, aspartame (NutraSweet). Aspartame is converted to phenylalanine in the gastrointestinal tract following ingestion. Chewable and effervescent formulations of acetaminophen products may also contain phenylalanine. The aspartame/phenylalanine content should be considered when these products are used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).

References:
  • "Product Information. Tylenol (acetaminophen)." McNeil Pharmaceutical, Raritan, NJ.
Acetaminophen, butalbital, caffeine, and codeine

Generic Name: acetaminophen / butalbital / caffeine / codeine

Brand Name: Fioricet with Codeine, Phrenilin with Caffeine and Codeine

Synonyms: Butalbital, Acetaminophen, Caffeine, and Codeine