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Kisqali Femara Co-Pack and Liver disease

Generic Name: letrozole / ribociclib
Dosage Forms: kit
Other Brand Names: Kisqali Femara Co-Pack 200 mg-25 mg Dose , Kisqali Femara Co-Pack 400 mg-25 mg Dose , Kisqali Femara Co-Pack 600 mg-25 mg Dose

Result of checking the interaction of drug Kisqali Femara Co-Pack and disease Liver disease for safety when used together.

Check result:

Kisqali Femara Co-Pack <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Letrozole is extensively metabolized by the liver. The pharmacokinetic disposition of letrozole has not been assessed in patients with severe hepatic impairment. No dosage modification is recommended for patients with mild to moderate hepatic impairment, however, therapy with letrozole should be administered cautiously to patients with severe hepatic impairment.

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