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Ketoconazole (Systemic) and QT prolongation

Result of checking the interaction of drug Ketoconazole (Systemic) and disease QT prolongation for safety when used together.

Check result:
Ketoconazole (Systemic) <> QT prolongation
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Most of the azole antifungals have been associated with prolongation of the QT interval. There have been postmarketing rare reports of QT prolongation, and torsade de pointes usually involving patients with risk factors such as structural heart disease, electrolyte abnormalities, and concomitant medications. These drugs should be administered with caution to patients with potentially proarrhythmic conditions. Concomitant use with other medications that have potential to increase the risk of cardiotoxicity should be avoided.

Ketoconazole (Systemic)

Generic Name: ketoconazole

Brand Name: Nizoral

Synonyms: Ketoconazole

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