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Ketek and Myasthenia gravis

Result of checking the interaction of drug Ketek and disease Myasthenia gravis for safety when used together.

Check result:

Ketek <> Myasthenia gravis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Telithromycin has been reported to exacerbate myasthenia gravis. Case reports suggest that it can occur even within a few hours after the first dose. Life-threatening acute respiratory failure with a rapid onset has occurred in patients with myasthenia gravis receiving telithromycin for respiratory tract infections. Therapy with telithromycin is not recommended in patients with myasthenia gravis unless no other therapeutic alternatives are available. If telithromycin is prescribed, patients must be closely monitored and advised to immediately discontinue the drug and seek medical attention if they experience exacerbation of their symptoms. Supportive measures should be instituted as medically necessary.

References:

"Product Information. Ketek (telithromycin)." Aventis Pharmaceuticals, Bridgewater, NJ.
Nieman RB, Sharma K, Edelberg H, Caffe SE "Telithromycin and myasthenia gravis." Clin Infect Dis 37 (2003): 1579

Ketek

Generic Name: telithromycin

Brand Name: Ketek

Synonyms: n.a.

What is Ketek?