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Kenalog (Triamcinolone Lotion) and Hyperadrenocorticism

Result of checking the interaction of drug Kenalog (Triamcinolone Lotion) and disease Hyperadrenocorticism for safety when used together.

Check result:
Kenalog (Triamcinolone Lotion) <> Hyperadrenocorticism
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of topical corticosteroids may precipitate or aggravate conditions of hyperadrenocorticism. Systemic absorption of these agents can produce reversible hypothalamic-pituitary-adrenal axis suppression. Systemic absorption, depends on the vehicle and concentration of the preparation, the size of the application area, the duration of administration, and whether or not occlusive dressings are used. Given equivalent doses, small children are generally at the greatest risk because of their larger skin surface to body mass ratios. Patients with an altered skin barrier or liver failure are also at increased risk. If possible, the use of highly potent agents (e.g., augmented betamethasone, clobetasol, diflorasone, and halobetasol) should be avoided in children and limited to small areas for 2 weeks in adults. The development of symptoms such as menstrual irregularities, acneiform lesions, cataracts and cushingoid features during topical corticosteroid therapy may indicate excessive use.

References:
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  • "Product Information. Cutivate (fluticasone)." Glaxo Wellcome, Research Triangle Park, NC.
  • "Product Information. Kenalog (triamcinolone topical)." Westwood Squibb Pharmaceutical Corporation, Buffalo, NY.
  • Ruiz-Maldonado R, Zapata G, Lourdes T, Robles C "Cushing's syndrome after topical application of corticosteroids." Am J Dis Child 136 (1982): 274-5
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  • "Product Information. Cordran (flurandrenolide topical)." Oclassen Pharmaceuticals Inc, Corona, CA.
  • "Product Information. Halog (halcinonide)." Bristol-Myers Squibb, Princeton, NJ.
  • "Product Information. Cloderm (clocortolone topical)" Hermal Pharmaceutical Labs Inc, Delmar, NY.
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  • Watson WA, Kalb RE, Siskin SB, Freer JP, Krochmal L "The safety of halobetasol 0.05% ointment in the treatment of psoriasis [published erratum appears in Pharmacotherapy 1991;11(3):preceding Table of Contents]." Pharmacotherapy 10 (1990): 107-11
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  • "Product Information. Ultravate (halobetasol)." Bristol-Myers Squibb, Princeton, NJ.
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  • "Product Information. Synalar (fluocinolone topical)." Syntex Laboratories Inc, Palo Alto, CA.
  • "Product Information. Aristocort Topical (triamcinolone topical)." Fujisawa, Deerfield, IL.
  • "Product Information. Dermatop (prednicarbate topical)." Janssen Pharmaceuticals, Titusville, NJ.
  • "Product Information. Elocon (mometasone topical)." Schering Corporation, Kenilworth, NJ.
  • "Product Information. Proctocream HC 2.5% (hydrocortisone topical)." Schwarz Pharma, Mequon, WI.
  • "Product Information. Topicort (desoximetasone topical)." Hoechst Marioin-Roussel Inc, Kansas City, MO.
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Kenalog (Triamcinolone Lotion)

Generic Name: triamcinolone topical

Brand Name: Cinolar, Kenalog, Oralone, Pediaderm TA, Triamcinolone Acetonide in Absorbase, Trianex, Triderm, Aristocort A, DermasilkRx SDS Pak, Dermasorb TA, DermaWerx SDS Pak, Triacet, Aricin, Aristocort R, Delta-Tritex, Flutex, Rx Triamcinolone, Aristocort Topical, Cinalog, Kenalog in Orabase, DermacinRx SilaPak

Synonyms: Kenalog

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