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Juxtapid Capsules and Liver impairment

Result of checking the interaction of drug Juxtapid Capsules and disease Liver impairment for safety when used together.

Check result:

Juxtapid Capsules <> Liver impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of lomitapide is contraindicated in patients with moderate or severe hepatic impairment (Child-Pugh B or C), and patients with active liver disease, including unexplained elevations of serum transaminases. Lomitapide increases hepatic fat, with or without concomitant increases in transaminases. Hepatic steatosis associated with the use of lomitapide may be a risk factor for progressive liver disease including steatohepatitis and cirrhosis. Patients with mild liver impairment should not exceed 40 mg daily as exposure can increase up to 50% compared with healthy volunteers.

Juxtapid Capsules

Generic Name: lomitapide

Brand Name: Juxtapid

Synonyms: Lomitapide

What is Juxtapid Capsules?