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Irinotecan liposomal and Liver impairment

Result of checking the interaction of drug Irinotecan liposomal and disease Liver impairment for safety when used together.

Check result:

Irinotecan liposomal <> Liver impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The metabolism of irinotecan liposomal has not been evaluated. Irinotecan is primary metabolized by the liver to a biologically active metabolite. The pharmacokinetic disposition of irinotecan liposomal in patients with hepatic impairment has not been formally assessed. Therapy with irinotecan liposomal should be administered cautiously to patients with or predisposed to compromised hepatic function. Clinical monitoring of hepatic function is recommended.

Irinotecan liposomal

Generic Name: irinotecan liposomal

Brand Name: Onivyde

Synonyms: Irinotecan (Liposomal)

What is Irinotecan liposomal?