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Iressa and Liver disease

Result of checking the interaction of drug Iressa and disease Liver disease for safety when used together.

Check result:

Iressa <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Gefitinib undergoes extensive hepatic metabolism. Obtain periodic liver function testing and withhold gefitinib for up to 14 days in patients with worsening liver function (Grade 2 or higher for ALT and/or AST elevations) and resume treatment when the adverse reaction fully resolves or improves to NCI CTCAE Grade 1. Permanently discontinue therapy in patients with severe hepatic impairment. Monitor adverse reactions when gefitinib is administered to patients with moderate and severe hepatic impairment.

Iressa

Generic Name: gefitinib

Brand Name: Iressa

Synonyms: n.a.

What is Iressa?