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Amantadine Hydrochloride and Seizure disorders
Result of checking the interaction of drug Amantadine Hydrochloride and disease Seizure disorders for safety when used together.
Check result:
Amantadine Hydrochloride <> Seizure disorders
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Amantadine may rarely precipitate or exacerbate seizure activity. Patients with epilepsy or predisposed to seizures should be monitored closely for increased seizure activity during therapy with amantadine.
References:
- "Product Information. Symmetrel (amantadine)." DuPont Pharmaceuticals, Wilmington, DE.
- Ing TS, Daugirdas JT, Soung LS, et al "Toxic effects of amantadine in patients with renal failure." Can Med Assoc J 120 (1979): 695-8
- Millet VM, Dreisbach M, Bryson YJ "Double-blind controlled study of central nervous system side effects of amantadine, rimantadine, and chlorpheniramine." Antimicrob Agents Chemother 21 (1982): 1-4
- Millet VM, Dreisbach M, Bryson YJ "Double-blind controlled study of central nervous system side effects of amantadine, rimantadine, and chlorpheniramine." Antimicrob Agents Chemother 21 (1982): 1-4
Amantadine Hydrochloride
Generic Name: amantadine
Brand Name: Gocovri, Osmolex ER, Symmetrel
Synonyms: Amantadine
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