Drug search by name

Integrilin and Renal dysfunction

Generic Name: eptifibatide
Dosage Forms: injection, solution
Other Brand Names: Integrilin

Result of checking the interaction of drug Integrilin and disease Renal dysfunction for safety when used together.

Check result:

Integrilin <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of eptifibatide is contraindicated in patients dependent of dialysis. Approximately 50% of eptifibatide is cleared by the kidney in patients with normal renal function. Total drug clearance is decreased by approximately 50% and steady-state plasma eptifibatide concentrations are doubled in patients with an estimated CrCl <50 mL/min. Therefore, the infusion dose should be reduced to 1 mcg/kg/min in such patients Clinical monitoring of renal function is recommended.

References: