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Insulin degludec and liraglutide and Renal dysfunction

Result of checking the interaction of drug Insulin degludec and liraglutide and disease Renal dysfunction for safety when used together.

Check result:

Insulin degludec and liraglutide <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

There have been reports of acute renal failure and worsening of chronic renal failure sometimes requiring hemodialysis in patients treated with GLP-1 receptor inhibitors. Some of these events occurred in patients without known underlying renal disease. These drugs should be used with caution in patients with renal impairment, especially during treatment initiation or dose escalation. Patients should be monitored, especially if they report severe gastrointestinal reactions such as nausea, vomiting, diarrhea, or dehydration. The frequency of gastrointestinal events is increased as renal function declines. There is limited clinical experience with most of these drugs in patients with severe renal impairment.

Insulin degludec and liraglutide

Generic Name: insulin degludec / liraglutide

Brand Name: Xultophy

Synonyms: Insulin Degludec and Liraglutide

What is Insulin degludec and liraglutide?