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Inotersen Subcutaneous and Hepatic impairment

Result of checking the interaction of drug Inotersen Subcutaneous and disease Hepatic impairment for safety when used together.

Check result:

Inotersen Subcutaneous <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Inotersen has not been studied in patients with moderate or severe hepatic impairment. Additionally, patients taking inotersen have shown elevation of hepatic enzymes. Monitor alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin at baseline and every four months during treatment. If a patient develops clinical signs or symptoms suggestive of hepatic dysfunction (e.g., unexplained nausea, vomiting, abdominal pain, fatigue, anorexia, or jaundice and/or dark urine), promptly measure serum transaminases and total bilirubin and interrupt or discontinue treatment with inotersen.

Inotersen Subcutaneous

Generic Name: inotersen

Brand Name: Tegsedi

Synonyms: Inotersen

What is Inotersen Subcutaneous?