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Imbruvica and Hepatic impairment

Result of checking the interaction of drug Imbruvica and disease Hepatic impairment for safety when used together.

Check result:

Imbruvica <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Ibrutinib is metabolized in the liver. In clinical trials, patients with hepatic impairment showed an increase in ibrutinib exposure following a single dose administration. It is recommended to monitor patients for signs of toxicity and follow dose modification as appropriate. The use of ibrutinib is not recommended in patients with moderate or severe hepatic impairment.

Imbruvica

Generic Name: ibrutinib

Brand Name: Imbruvica

Synonyms: n.a.

What is Imbruvica?