Drug search by name

Ifosfamide and Mesna Injection and Autoimmune disorders

Result of checking the interaction of drug Ifosfamide and Mesna Injection and disease Autoimmune disorders for safety when used together.

Check result:

Ifosfamide and Mesna Injection <> Autoimmune disorders

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Mesna is a thiol (SH) compound. Hypersensitivity reactions including anaphylaxis have occurred in patients with autoimmune disorders, the majority of whom received high dosages of mesna orally. Therapy with mesna should be administered cautiously in patients with autoimmune disorders.

References:

Reinhold-Keller E, Mohr J, Christophers E, Nordmann K, Gross WL "Mesna side effects which imitate vasculitis." Clin Investig 70 (1992): 698-704
Seidel A, Andrassy K, Ritz E, Kasser U, Lemmel EM "Allergic reactions to mesna." Lancet 338 (1991): 381
Lang E, Goos M "Hypersensitivity to mesna." Lancet 2 (1985): 329
Zonzits E, Aberer W, Tappeiner G "Drug eruptions from mesna. After cyclophosphamide treatment of patients with systemic lupus erythematosus and dermatomyositis." Arch Dermatol 128 (1992): 80-2
"Product Information. Mesnex (mesna)." Bristol-Myers Squibb, Princeton, NJ.

Ifosfamide and Mesna Injection

Generic Name: ifosfamide / mesna

Brand Name:

Synonyms: n.a.

What is Ifosfamide and Mesna Injection?