Drug search by name

Hydrochlorothiazide and aliskiren and Renal impairment

Result of checking the interaction of drug Hydrochlorothiazide and aliskiren and disease Renal impairment for safety when used together.

Check result:

Hydrochlorothiazide and aliskiren <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Renal function should be monitored periodically in patients treated with aliskiren, as changes can occur including acute renal failure. Patients on aliskiren whose renal function may depend in part of the RAAS (renin-angiotensin-aldosterone system), such as patients with renal artery stenosis, severe heart failure, or postmyocardial infarction may be at higher risk for developing acute renal failure. Treatment should be discontinued in any patients who develop clinically significant decrease in renal function. Patients with renal impairment should be observed closely. The safety and effectiveness of aliskiren have not been established in patients with severe renal impairment (CrCl < 30 mL/min), as these patients were excluded from clinical trials.

Hydrochlorothiazide and aliskiren

Generic Name: aliskiren / hydrochlorothiazide

Brand Name: Tekturna HCT

Synonyms: Aliskiren and Hydrochlorothiazide

What is Hydrochlorothiazide and aliskiren?