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Glycopyrrolate and indacaterol inhalation and Arrhythmias

Result of checking the interaction of drug Glycopyrrolate and indacaterol inhalation and disease Arrhythmias for safety when used together.

Check result:
Glycopyrrolate and indacaterol inhalation <> Arrhythmias
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with tachycardia should be supervised closely during treatment with anticholinergic agents. Tachycardia is produced by blocking normal vagal inhibition of the SA node. Paradoxically, bradycardia may occur due to central vagal stimulation which may occur prior to peripheral cholinergic blockade.

References:
  • Blumensohn R, Razoni G, Shalev A, Munitz H "Bradycardia due to trihexyphenidyl hydrochloride." Drug Intell Clin Pharm 20 (1986): 786-7
  • "Product Information. Artane (trihexyphenidyl)." Lederle Laboratories, Wayne, NJ.
  • "Product Information. Cogentin (benztropine)." Merck & Co, Inc, West Point, PA.
  • Voinov H, Elefante V, Mujica R "Sinus bradycardia related to the use of benztropine mesylate." Am J Psychiatry 149 (1992): 711
Glycopyrrolate and indacaterol inhalation

Generic Name: glycopyrrolate / indacaterol

Brand Name: Utibron Neohaler

Synonyms: Glycopyrrolate and indacaterol (inhalation), Indacaterol and Glycopyrrolate

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