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Flumazenil Injection and Psychoses

Result of checking the interaction of drug Flumazenil Injection and disease Psychoses for safety when used together.

Check result:
Flumazenil Injection <> Psychoses
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Panic attacks have been induced by flumazenil in patients with a history of panic attacks. Emotional lability, including crying, depersonalization, euphoria, depression, dysphoria and paranoia have also been reported. Therapy with flumazenil should be administered cautiously in patients with or predisposed to psychosis, particularly panic attacks.

References:
  • Seebach J, Jost R "Flumazenil-induced psychotic disorder in hepatic encephalopathy." Lancet 339 (1992): 488-9
  • "Flumazenil." Med Lett Drugs Ther 34 (1992): 66-8
  • "Product Information. Romazicon (flumazenil)." Roche Laboratories, Nutley, NJ.
  • Griffiths RR, Evans SM, Guarino JJ, Roache JD, Furman WR, Liebson I, Schwam EM "Intravenous flumazenil following acute and repeated exposure to lorazepam in healthy volunteers: antagonism and precipitated withdrawal." J Pharmacol Exp Ther 265 (1993): 1163-74
Flumazenil Injection

Generic Name: flumazenil

Brand Name: Romazicon

Synonyms: Flumazenil

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