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Ezetimibe and simvastatin and Renal impairment

Result of checking the interaction of drug Ezetimibe and simvastatin and disease Renal impairment for safety when used together.

Check result:
Ezetimibe and simvastatin <> Renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

No dosage adjustment of ezetimibe is necessary in patients with renal impairment. However, when ezetimibe therapy is given in combination with simvastatin in patients with moderate to severe renal impairment (estimated glomerular filtration rate <60 mL/min/1.73 m2), doses of simvastatin exceeding 20 mg should be used with caution and close monitoring is recommended.

Ezetimibe and simvastatin

Generic Name: ezetimibe / simvastatin

Brand Name: Vytorin

Synonyms: Ezetimibe and Simvastatin

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