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Epirubicin Hydrochloride and Heart disease/toxicity

Result of checking the interaction of drug Epirubicin Hydrochloride and disease Heart disease/toxicity for safety when used together.

Check result:

Epirubicin Hydrochloride <> Heart disease/toxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of epirubicin is contraindicated in patients with severe myocardial insufficiency, recent myocardial infarction, and severe arrhythmias. Myocardial toxicity, manifested in its most severe form by potentially fatal congestive heart failure (CHF), may occur either during therapy with epirubicin or months to years after termination of therapy. Risk factors may increase the risk of cardiac toxicity. Cardiac toxicity with epirubicin may occur at lower cumulative doses whether or not cardiac risk factors are present, so extreme caution is advised. Initial treatment with epirubicin should be preceded by a careful baseline assessment of cardiac function as measured by left ventricular ejection function (LVEF). Close cardiac monitoring during treatment is suggested.

Epirubicin Hydrochloride

Generic Name: epirubicin

Brand Name: Ellence, Pharmorubicin Pfs, Pharmorubicin RDF

Synonyms: Epirubicin, EPIrubicin

What is Epirubicin Hydrochloride?