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Endrate and Cardiovascular dysfunction

Generic Name: edetate disodium (edta)
Dosage Forms: Injection
Other Brand Names:

Result of checking the interaction of drug Endrate and disease Cardiovascular dysfunction for safety when used together.

Check result:

Endrate <> Cardiovascular dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Severe cardiac arrhythmias associated with EDTA disodium are due to decreased serum calcium. EDTA also exerts a negative inotropic effect on the heart and can exacerbate congestive heart failure. EDTA disodium functions to reduce serum concentrations of calcium by forming stable soluble complexes with calcium. EDTA also chelates zinc, magnesium, and other trace metals and increases potassium excretion in the urine. Therapy with EDTA disodium should be used with caution in patients with limited cardiac reserve, congestive heart failure or arrhythmia. Clinical monitoring of cardiac function and electrolytes (including calcium, potassium, and magnesium) is recommended.

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