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Elspar and Pancreatic dysfunction
Result of checking the interaction of drug Elspar and disease Pancreatic dysfunction for safety when used together.
Check result:
Elspar <> Pancreatic dysfunction
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:The use of asparaginase is contraindicated in patients with pancreatitis or a history of pancreatitis. Pegaspargase can cause decreased insulin synthesis or may cause inflammation and/or necrosis of cells of the pancreas. Fulminant and fatal pancreatitis has occurred. Clinical monitoring of pancreatic function, including serum amylase levels, is recommended.
References:
- "Product Information. Elspar (asparaginase)." Merck & Co, Inc, West Point, PA.
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