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Edetate calcium disodium and Renal dysfunction

Generic Name: edetate calcium disodium
Dosage Forms: n.a.
Other Brand Names: Calcium Disodium Versenate

Result of checking the interaction of drug Edetate calcium disodium and disease Renal dysfunction for safety when used together.

Check result:

Edetate calcium disodium <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of calcium EDTA is contraindicated in patients with anuria and active renal disease. Dose-related nephrotoxicity (usually reversible) associated with EDTA has included dysuria, oliguria, proteinuria, large renal epithelial cells in urine, renal insufficiency/failure, and acute tubular necrosis. Impaired renal function decreases the elimination of EDTA and may increase its nephrotoxicity. Adequate hydration (avoid excess hydration in patients with lead encephalopathy) and established urine flow prior to initiation of EDTA therapy is necessary. Clinical monitoring of renal function and calcium, phosphorus, and zinc levels is recommended.

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