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Echothiophate Iodide and Down's syndrome

Generic Name: echothiophate iodide ophthalmic
Dosage Forms: n.a.
Other Brand Names: Phospholine Iodide

Result of checking the interaction of drug Echothiophate Iodide and disease Down's syndrome for safety when used together.

Check result:

Echothiophate Iodide <> Down's syndrome

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Topically applied cholinesterase inhibitors are systemically absorbed, with the potential for producing rare but clinically significant systemic effects, including central nervous system disturbances such as confusion and seizures. Children with Down's syndrome may be particularly susceptible to the CNS effects of these drugs. Echothiophate, specifically, has also been reported to cause hyperactivity in these children. Therapy with ophthalmic cholinesterase inhibitors, particularly the long-acting ones (e.g., demecarium and echothiophate), should be administered cautiously in children with Down's syndrome.

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