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Dobutamine in Dextrose and Hypotension

Result of checking the interaction of drug Dobutamine in Dextrose and disease Hypotension for safety when used together.

Check result:
Dobutamine in Dextrose <> Hypotension
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of dobutamine and arbutamine has been infrequently associated with significant hypotension especially in dehydrated patients secondary to beta-2 mediated vasodilation. Hypovolemia should be corrected before administering dobutamine or arbutamine. Blood pressure and ECG should be monitored at regular intervals. Monitoring of cardiac output and pulmonary wedge pressure may also be desired.

References:
  • Heinle SK, Tice FD, Kisslo J "Hypotension during dobutamine stress echocardiography: is it related to dynamic intraventricular obstruction?" Am Heart J 130 (1995): 314-7
  • "Product Information. GenESA (arbutamine)." Gensia Inc, San Diego, CA.
  • "Product Information. Dobutrex (dobutamine)." Lilly, Eli and Company, Indianapolis, IN.
  • Rosamond TL, Vacek JL, Hurwitz A, Rowland AJ, Beauchamp GD, Crouse LJ "Hypotension during dobutamine stress echocardiography: initial description and clinical relevance." Am Heart J 123 (1992): 403-7
Dobutamine in Dextrose

Generic Name: dobutamine

Brand Name: Dobutrex

Synonyms: Dobutamine, DOBUTamine

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